Jevtana injection singledose vial requires two dilutions prior to administration see. Dexamethasone sodium phosphate injection, usp is a sterile solution of dexamethasone sodium phosphate, and is supplied in 4 mg ml and 10 mg ml. Dec 15, 2019 dexamethasone sodium phosphate injection, usp is a watersoluble inorganic ester of dexamethasone which produces a rapid response even when injected intramuscularly. An alternative regimen of 20 mg by intravenous injection initially, followed by continuous intravenous infusion of 3 mgkg bodyweight per 24 hours, has been suggested. Ddavp is contraindicated in patients with moderate to severe renal impairment defined as a creatinine clearance below 50mlmin.
If chickenpox develops, treatment with antiviral agents should be. Also administer dexamethasone in the evenings on days 3 and 4. Highlights of prescribing information for all patients. Methylprednisolone injection fda prescribing information.
Dexamethasone sodium phosphate injection can be given directly from the vial, or it can be added to sodium chloride injection or dextrose injection and administered by intravenous drip. In this pooled safety population, injectionsite reactions occurred in 8% of patients, including grade 2 reactions in 0. Dexamethasone sodium phosphate injection, usp is a watersoluble inorganic ester of dexamethasone which produces a rapid response even when injected intramuscularly. The use of dexamethasone sodium phosphate injection in active. Highlights of prescribing information these highlights do not. Increased dosage of rapidly acting corticosteroids is indicated in patients on corticosteroid therapy. Dexamethasone sodium phosphate injection, usp dexamethasone. See full prescribing information for recommended dosages of concomitant dexamethasone and 5ht3 antagonist for hec and mec. Establish safeguards and alerts at each step of the medication use process ordering, verifying, dispensing, and administration. Dexamethasone sodium phosphate injection, usp mylan.
Dexamethasone is often injected into a muscle or into a vein through an iv. Dbl dexamethasone sodium phosphate, solution for injection. Your dosage needs may change if you have any unusual stress such as a serious illness, fever or infection, or if you have surgery or a medical emergency. Docetaxel injection must not be given to patients who have a history of severe. Latent disease may be activated or there may be an exacerbation of intercurrent infections due to pathogens, including. Dexamethasone sodium phosphate injection, usp fresenius kabi. Dexamethasone tablets usp, dexamethasone oral solution, and dexamethasone intensol oral solution concentrate description dexamethasone tablets 0. Dexamethasone sodium phosphate injection, 10 mgml for intravenous and intramuscular injection only. This may be repeated in 2 to 6 hours if shock persists. These local reactions occurred a median of 7 minutes range. Highlights of prescribing information emend capsules and. If required for intravenous infusion, dexamethasone phosphate may be diluted with glucose or sodium. Highlights of prescribing information contraindications these. Each applicator can only be used for the treatment of a single eye.
Dexamethasone sodium phosphate injection, usp dailymed. It is practically insoluble in water, sparingly soluble in anhydrous ethanol, slightly soluble in methylene chloride. Each 1 ml of precedex contains 118 mcg of dexmedetomidine hcl equivalent to 100 mcg dexmedetomidine base and 9 mg of sodium chloride in water. Administer cerenia injectable solution intravenously over 12 minutes or subcutaneously at 1 mgkg 0. Cytarabine injection, an antineoplastic, is a sterile solution of cytarabine for intravenous and subcutaneous use which contains no preservative and is available in 20 mgml mg50 ml pharmacy bulk package. Name, address, and telephone of the responsible party supp lie r. Ddavp injection 4 mcgml is contraindicated in individuals with known hypersensitivity to desmopressin acetate or to any of the components of ddavp injection 4 mcgml.
If no chemotherapy is given on days 2 and 3, administer emend in morning. Mylan manufactures dexamethasone sodium phosphate injection, usp dexamethasone sodium phosphate in strengths of 4 mg1 ml 4 mgml20 mg5 ml 4 mgml100 mg10 ml 10 mgml120 mg30 ml 4 mgml. Administer emend 1 hour prior to chemotherapy on days 1, 2, and 3. The most frequent 1% injectionsite reaction was injection site erythema. Tablets and injectable solution animal safety antiemetic. Precedex is supplied as a clear, colorless, isotonic solution with a ph of 4. Cytoxan tablets cyclophosphamide tablets, usp are for oral use and contain 25 mg or 50 mg cyclophosphamide anhydrous. Cytoxan cyclophosphamide for injection, usp cytoxan tablets.
Highlights of prescribing information these highlights do not include all the information needed to use xgeva safely and effectively. See the respective package inserts for vzig and ig for. Administer emend for injection as an intravenous infusion on day 1. Kyprolis given with dexamethasone kept the disease from getting worse longer than velcade and dexamethasone median of 18. Dexamethasone is a white or almost white, crystalline powder. See cerenia tablets package insert for complete prescribing information. Administer dexamethasone 30 minutes prior to chemotherapy treatment on day 1 and in the morning on days 2 through 4. Dexamethasone injection fda prescribing information, side. If a local anesthetic is used prior to injection of methylprednisolone acetate injectable suspension, the anesthetic package insert should be read carefully and all the precautions observed. Dbltm dexamethasone sodium phosphate injection 4 mg ml solution for injection. A 50% dosage reduction of dexamethasone on days 1 and 2 is recommended to account for a drug interaction with aprepitant.
You need to take it regularly to get the maximum benefit. Glucagen should be reconstituted with 1 ml of sterile water for reconstitution if supplied or 1 ml of sterile water for injection, usp. Dexamethasone sodium phosphate usp, c22h28fna2o8p, has a molecular weight of 516. Aug 01, 2019 dexamethasone sodium phosphate injection usp is a sterile, clear, colorless solution, free from visible particles and a watersoluble inorganic ester of dexamethasone which produces a rapid response even when injected intramuscularly.
Other medications in addition to dexamethasone, complete administration of the following medications 45 to 90 minutes prior to empliciti infusion. Highlightsof prescribing information kyprolis safely and. Dexamethasone phosphate 4mgml solution for injection kern. Using a syringe, withdraw all of the sterile water for reconstitution if supplied or 1 ml sterile water for injection, usp and inject into the glucagen vial. Dexamethasone sodium phosphate solution for injection 4 mgml or 10 mgml may be added to 5% dextrose injection or 0. The recommended dosage of emend for injection, dexamethasone, and a 5ht.
If parenteral promethazine must be used, providers and clinicians must follow recommendations per the package insert, ismp, and va medsafe. Kyprolis is approved for use in combination with dexamethasone or with lenalidomide plus dexamethasone, which are other medicines used to treat multiple myeloma. Dexamethasone sodium phosphate injection, usp intended use of the produ ct use of the substancemixture. Kenalog 40 injection triamcinolone acetonide injectable suspension, usp is a synthetic glucocorticoid corticosteroid with antiinflammatory action. Each 1 ml of precedex contains 118 mcg of dexmedetomidine hcl equivalent to 100 mcg dexmedetomidine base and 9. Patients should be instructed to report any symptoms suggestive of endophthalmitis without delay. In the single agent multiple myeloma study of bortezomib for injection vs dexamethasone, the mean platelet count nadir measured was approximately 40% of baseline. Xgeva denosumab injection, for subcutaneous use initial u. As is standard practice, and as stated in the dexamethasone sodium phosphate injection, usp product package insert, parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Amphotericin b injection and potassiumdepleting agents. Dexamethasone sodium phosphate injection, usp 4 mgml is a sterile solution for intravenous, intramuscular, intraarticular, intralesional and soft tissue administration. Dexamethasone injection is usually given for only a few days. Each ml of ciprodex contains ciprofloxacin hydrochloride equivalent to 3 mg ciprofloxacin base, 1 mg. Kyprolis carfilzomib for relapsed multiple myeloma treatment.
Emendfor injection 150mg intravenously over 20 to 30 minutes dexamethasone 12 mg orally 5ht3 antagonist see selected 5ht3 antagonist prescribing information for the recommended dosage administer dexamethasone 30 minutes prior to chemotherapy treatment on day 1. In a clinical trial that collected information about injection site pain and tenderness from patient diaries, pain with or without tenderness at the injection site was reported by 91 of 456 20% of patients treated with sustol 10 mg, and an additional 50 of 456 11% of patients reported tenderness without pain. For prevention of vomiting in dogs 4 months of age and older caused by emetogenic medications or chemotherapeutic agents. Dexamethasone sodium phosphate injection, usp 10 mgml is for intravenous or intramuscular use only. Dexamethasone sodium phosphate, a synthetic adrenocortical steroid, is a white or slightly yellow crystalline powder. Highlights of prescribing information qt prolongation has. Dexamethasone sodium injection anda 084916 s066 fda. Cytoxan cyclophosphamide for injection, usp cytoxan. Dbltm dexamethasone sodium phosphate injection 4 mgml solution for injection.
It is sometimes used in combination with other medications to treat symptoms of low corticosteroid levels lack of certain substances that are usually produced by the body and are needed for normal. The area around the injection site is prepared in a sterile way and a wheal at the site made with 1 percent procaine hydrochloride solution. Dexamethasone tablets usp, dexamethasone oral solution, and. Dexamethasone sodium phosphate injection, usp is available in 4 mgml. Dexamethasone kern pharma 4 mgml solution for injection generic medicinal product. Emend fosaprepitant dimeglumine for injection label. Refer to product insert for usage instructions and product information. Antiemetic prophylaxis is recommended and can be given orally or intravenously as needed see warnings and precautions 5. Mylan manufactures dexamethasone sodium phosphate injection, usp dexamethasone sodium phosphate in strengths of 4 mg1 ml 4 mgml20 mg5 ml 4 mgml100 mg10 ml 10 mgml120 mg30 ml 4. It is freely soluble in water and is exceedingly hygroscopic. See the respective package inserts for vzig and ig for complete prescribing information. For more information please refer to the package leaflet. Alimta pemetrexed for injection healthcare provider site.
Hypersensitivity reactions require immediate discontinuation of the docetaxel injection infusion and administration of appropriate therapy see warnings and precautions 5. Dexamethasone sodium phosphate solution for injection 4 mgml or 10 mgml may be given directly from the vial. A healthcare provider will give you this injection. Mar 01, 2020 if a local anesthetic is used prior to injection of methylprednisolone acetate injectable suspension, the anesthetic package insert should be read carefully and all the precautions observed. Dexamethasone sodium phosphate injection, usp can be given directly from the vial, or it can be added to sodium chloride injection or dextrose injection and administered by intravenous drip. A 50% dosage reduction of dexamethasone on days 1 and 2 is recommended to account for a. Dexamethasone injection is also used to treat certain conditions that affect the blood, skin, eyes, thyroid, kidneys, lungs, and nervous system. Dexamethasone sodium phosphate injection, usp 4 mgml. When oral therapy is not feasible and the strength, dosage form, and route of administration of the drug reasonably. This product, like many other steroid formulations. Use a lower starting dose for patients with moderate or severe hepatic impairment. Cytoxan tablets cyclophosphamide tablets, usp are for oral use and contain 25 mg or 50 mg cyclophosphamide. Official hcp website darzalex faspro daratumumab and. Randomized, doubleblind, phase 3 study of pembrolizumab or placebo plus pemetrexed and platinum as firstline therapy for metastatic nsclc.
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